The search for new treatments and medications for weight loss is an important topic for many Americans. Two-thirds of adult Americans are overweight. The struggle to lose and maintain a healthy weight can be incredibly frustrating. These individuals often feel isolated and alone in their constant battle to lose weight, but most Americans share this same struggle. Obesity is a complex disease; trying to eat healthily and exercise should always be a priority, but many patients struggle to lose weight despite these efforts. Fortunately, some new players are in the market to help our patients lose and maintain their weight.